Transplanting a Kidney Is the Easy Part

Transplanting Kidneys from Deceased Donors With Severe Acute Kidney Injury.

Our aim was to determine outcomes with transplanting kidneys from deceased donors with acute kidney injury, defined as a donor with terminal serum creatinine ≥2.0 mg/dL, or a donor requiring acute renal replacement therapy. We included all patients who received deceased donor kidney transplant from June 2004 to October 2013. There were 162 AKI donor transplant recipients (21% of deceased donor ...

Clinical results from transplanting incompatible live kidney donor/recipient pairs using kidney paired donation.

CONTEXT First proposed 2 decades ago, live kidney paired donation (KPD) was considered a promising new approach to addressing the shortage of organs for transplantation. Ethical, administrative, and logistical barriers initially proved formidable and prevented the implementation of KPD programs in the United States. OBJECTIVE To determine the feasibility and effectiveness of KPD for the manag...

Development is easy

Kinetochores hold on with a ring complex that links a budding yeast kinetochore to a microtubule (MT) forms a ring around the MT, based on structures from two groups. The ring may help kinetochores to keep hold of an MT, even as the MT shrinks towards the spindle pole during anaphase. Stephen Harrison (Harvard Medical School, Boston, MA) and Peter Sorger (MIT, Cambridge, MA) are hoping to analy...

Is alpha-conversion easy?

λx.S ◦A instead of λx.(A[S]) S ◦ λx.A instead of (λx.A)[S] λx.S2 ◦ S1 ◦ A instead of λx.(A[S1][S2]) S2 ◦ λx.S1 ◦ A instead of (λx.A[S1])[S2] S2 ◦ S1 ◦ λx.A instead of (λx.A)[S1][S2] And so on. Far fewer parentheses. And very close to notation of category theory. If we have composition of substitutions (not in my calculus), then λx.(S2 ◦ S1) ◦ A means λx.(A[S1 ◦ S2]) From the point of view of ca...

Arithmetic Is Easy